COVID-19 and Gender Role in Unemployment: How Women in Special Capital Region of Jakarta is Less Likely to be Unemployed During Economic Disturbance

The gender gap that occurs in Special Capital Region of Jakarta, between men and women has an impact on aspects of employment related to labor absorption. Increasing the number of optimal employment opportunities, both in terms of productivity and efficiency, can determine the success of economic development in a region. This study was conducted to see how likely it is that women are unemployed, in relation to the employment aspect in Special Capital Region of Jakarta which is based on secondary data from BPS and analyzed with a descriptive quantitative approach. The results showed that the open unemployment rate (TPT) in Special Capital Region of Jakarta in 2019-2020 experienced a significant increase in 2020, namely 4.86% for men and 4.5% for women. Different results are shown in the variable labor force participation rate (TPAK), which tends to experience a fluctuating trend with the participation rate of men being higher than women. In general, the COVID-19 pandemic has an impact on employment, which in turn has an impact on unemployment. During the COVID-19 pandemic, the unemployment rate was dominated by men, due to the high wages of men compared to women. In addition, women's labor force participation rates are relatively low compared to men's, causing women to have little chance of being unemployed. Female workers have higher resilience than male workers, this is due to the higher saturation of women in informal economic activities with entrepreneurship. Entrepreneurial activities tend to have more resilience than formal workers because there is no risk of termination of employment from the employer. © The Authors, published by EDP Sciences.

Association between community perception and willingness to vaccinated againts COVID-19 in Surakarta, Central Java, Indonesia

Background: Covid-19 has been declared a pandemic since March 2020 until now, so the government requires the provision of a covid-19 vaccine for all people. The government's vaccination campaign has received various responses from the public, some people accept and some reject the Covid-19 vaccine. This study aims to determine the relationship between public perception of the acceptance of the COVID-19 vaccine in Surakarta. Subjects and Methods: The cross sectional study was conducted in Surakarta. A sample of 65 people aged >12 years was selected by random sampling. The dependent variable was the willingness to receive the covid-19 vaccine. Tthe independent variable was perception. Data was collected by online questionnaire (google form). Data were analyzed by chi square test.

Anthocyanin, tartaric acid, ascorbic acid of roselle flower (Hibiscus sabdariffa L.) for immunomodulatory adjuvant therapy in oral manifestation coronavirus disease-19: An immunoinformatic approach

Context: Oral manifestations that arose from COVID-19 infection often causes morbidity and systemic drug administration is less effective. Roselle flower (Hibiscus sabdariffa) is one of the plants that is often used in infusion as it gives health benefits. Hence, H. sabdariffa may benefit from adjuvant therapy to treat oral manifestation due to COVID-19. Aims: To investigate the potential of H. sabdariffa anthocyanins, tartaric acid, and ascorbic acid chemical compounds as antiviral, anti-inflammatory, antioxidant, and increasing tissue regeneration in oral manifestation due to COVID-19 infection in silico. Methods: Chemical compounds consisted of anthocyanins, (+)-tartaric acid, and ascorbic acid beside target proteins consisted of ACE2-spike, Foxp3, IL-10, IL6, IL1β, VEGF, FGF-2, HSP70, TNFR and MDA-ovalbumin were obtained from the database, ligand samples were selected through absorption, distribution, metabolism, excretion and toxicology analysis, then molecular docking simulations, identification of protein-ligand interactions, and 3D visualization were performed. Results: Anthocyanins, tartaric acid, and ascorbic acid are the active compounds in H. sabdariffa, which act as antioxidants. The activity of anthocyanin compounds is higher than other compounds through value binding affinity, which is more negative and binds to specific domains of target proteins by forming weak binding interactions that play a role in biological responses. Anthocyanins have the most negative binding energy compared to tartaric-acid and ascorbic acid. Conclusions: Anthocyanins act as antioxidants;this mechanism increases heat shock protein-70 (HSP70), which may play an important role in increasing wound regeneration of oral manifestation in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as documented in silico.